Acetal Formation (Forward and Reverse Directions)

All Videos:

Acetal Formation (Forward and Reverse Directions)

21385 views (youtube + vimeo)

Practice Resources:

Guided Worksheet(s) + Solutions:

- Rxn Practice of Ketones & Aldehydes, Part 1. Getting Them Down | Solution

- Rxn Practice of Ketones and Aldehydes, Part 2—A Bit More Challenging | Solution

Worksheet Solutions Walkthrough(s):

- Rxn Practice of Ketones & Aldehydes, Part 1. Getting Them Down

- Rxn Practice of Ketones & Aldehydes, Part 2. Making Them Harder

Series Study Guide:

This study guide isn't available currently, but Joe is working on it!

Description

https://joechem.io/videos/33 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link). In this video, we go through Acetal Formation from a carbonyl, both the forward and reverse directions. Just like hydrate formation, trust me when I say knowing both directions like the back of your hand will pay dividends come test time.

Tags: ketone aldehyde equilibrium acetal free acidic environment carbonyl

Comments:

Eli • 7 years ago

At 8:55, why can't we just deprotinate the water group intramolecularly with the methoxy group? Kind of like a hydride shift in a way

REPLY
- Joe Del Nano • 7 years ago
  
  Hey Eli, You can absolutely do the intramolecular acid base reaction and have the oxygen in the methoxy deprotonate the oxygen in the water (on the structure): For the sake of the mechanism, i just wanted to be very clear and show all the steps but either works!
  
  REPLY