Nucleophilic Attack Using the Alpha Carbon

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https://joechem.io/videos/129 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link) In this video, we revisit the alpha carbon and talk about how we can perform nucleophilic attack and acid base reactions at the alpha position. In the midst of aldol reactions/condensations, Michael Additions, and Robinson Annulations, it's easy to forget this fundamental functionality at the alpha carbon (to perform Sn2, that is). We revisit enolates and also bring back our old friend the enamine, so it may be helpful to review the past video on enamines here on jOeCHEM (linked below). Enamine video: https://joechem.io/videos/35


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