Using Terminal Alkynes as Nucleophiles

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Practice Resources:

Guided Worksheet(s) + Solutions:
Worksheet Solutions Walkthrough(s):
-   Alkyne Reactions and Keto-Enol Tautomerism
-   Cumulative Synthesis
Series Study Guide:

This study guide isn't available currently, but Joe is working on it!
Description

https://joechem.io/videos/95 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link). In this video, we look at how we can use acetylide (or any terminal alkyne that has been deprotonated) as a nucleophile and attack carbonyls and perform Sn2.

Tags:  alkyne acid-base SN2 nucleophile carbonyl

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